abstract：:Obesity is increasing in epidemic proportions globally while current therapies continue to be suboptimal. In this investigation, weight loss in obese individuals after 24 weeks with different nutrition interventions was compared. The impact of intervention intensity was assessed. Inclusion criteria were established an...

journal_title：Advances in therapy

authors： Anderson JW,Luan J,Høie LH

更新日期：2004-03-01 00:00:00

abstract：:The tolerability of brimonidine tartrate 0.15%--referred to as bromonidine-Purite 0.15% in this study--was compared with brimonidine tartrate 0.2% in irritated eyes of healthy volunteers as well as patients with glaucoma or ocular hypertension (N=20) in a 2-week, single-center, randomized, double-masked, crossover stu...

journal_title：Advances in therapy

authors： Mundorf T,Wilcox KA,Ousler GW 3rd,Welch D,Abelson MB

更新日期：2003-11-01 00:00:00

abstract：:This 6-month randomized study evaluated the safety and efficacy of sibutramine in 57 overweight Hispanic patients with hypertension. Following a 2-week washout to confirm the diagnosis of hypertension, antihypertensive medication was adjusted to achieve a blood pressure less than 140/90 mm Hg before institution of eit...

journal_title：Advances in therapy

authors： Fanghänel G,Cortinas L,Sánchez-Reyes L,Gómez-Santos R,Campos-Franco E,Berber A

更新日期：2003-03-01 00:00:00

abstract：:Permixon, the lipidosterolic extract of Serenoa repens, is widely used for the treatment of symptoms associated with benign prostatic hyperplasia (BPH). This open study assessed the efficacy and tolerability of Permixon 160 mg twice daily administered for 2 years. One hundred fifty-five men with clinically diagnosed B...

journal_title：Advances in therapy

authors： Pytel YA,Vinarov A,Lopatkin N,Sivkov A,Gorilovsky L,Raynaud JP

更新日期：2002-11-01 00:00:00

abstract：:This study was conducted to determine the reasons for the choice of self-prescribed laxatives and to acquire information on how they were used and tolerated. From November 1999 to February 2000, 70 pharmacies, uniformly located throughout the Campania region of southern Italy, distributed a questionnaire to purchasers...

journal_title：Advances in therapy

authors： Motola G,Mazzeo F,Rinaldi B,Capuano A,Rossi S,Russo F,Vitelli MR,Rossi F,Filippelli A

更新日期：2002-09-01 00:00:00

abstract：:In a multicenter, open-label evaluation, 1098 patients with ocular itching and a history of perennial or seasonal allergic conjunctivitis instilled one drop of nedocromil sodium 2% twice daily in each eye. Ocular symptoms, signs, and global improvement were assessed at baseline and 1 month; satisfaction scores, qualit...

journal_title：Advances in therapy

authors： Tauber J,Alocril Community Allergy Trial Study Group.

更新日期：2002-03-01 00:00:00

abstract：:In a randomized, controlled, double-blind trial, 70 patients (mean age, 49.7 years) suffering from mild to moderate depression received one tablet of either St. John's Wort (Hypericum perforatum) extract (Calmigen) or fluoxetine hydrochloride (Prozac) twice a day for 6 weeks. Efficacy was determined according to the 1...

journal_title：Advances in therapy

authors： Behnke K,Jensen GS,Graubaum HJ,Gruenwald J

更新日期：2002-01-01 00:00:00

abstract：:The lipid-lowering effect of a carob pulp preparation rich in insoluble dietary fiber and polyphenols was investigated in a noncomparative, open-label pilot study. Over 8 weeks, 47 volunteers with moderate hypercholesterolemia (total cholesterol 232-302 mg/dL) consumed 15 g of carob per day in three products (breakfas...

journal_title：Advances in therapy

authors： Zunft HJ,Lüder W,Harde A,Haber B,Graubaum HJ,Gruenwald J

更新日期：2001-09-01 00:00:00

abstract：:This 4-week double-blind, placebo-controlled study assessed the efficacy of impulse magnetic-field therapy for insomnia. One hundred one patients were randomly assigned to either active treatment (n = 50) or placebo (n = 51) and allocated to one of three diagnostic groups: (1) sleep latency; (2) interrupted sleep; or ...

journal_title：Advances in therapy

authors： Pelka RB,Jaenicke C,Gruenwald J

更新日期：2001-07-01 00:00:00

abstract：:Intensive postremission chemotherapy has produced disease-free survival comparable to that of bone marrow transplantation in patients with acute myelogenous leukemia (AML), but its efficacy was unknown in Taiwan. We assessed the efficacy of intensive postremission chemotherapy, consisting of high-dose arabinoside-C (H...

journal_title：Advances in therapy

authors： Hsu HC,Gau JP,Liu JM,Chau WK,Ho CH

更新日期：2001-03-01 00:00:00

abstract：:Data from the Framingham Heart Study and risk-appraisal models were used to develop a Coronary Heart Disease (CHD) Risk Factor Calculator for early identification of high-risk individuals. The Calculator was tested at an employee health fair for a large northeastern US corporation. Of the 590 employees who registered ...

journal_title：Advances in therapy

authors： Day D

更新日期：2001-01-01 00:00:00

abstract：:Eupatorium laevigatum Lam. is a plant common to the central region of Brazil, where it is a widely used remedy for lesions such as buccal aphthae. These painful inflammatory ulcers affect 50% of the general population. For the first part of this two-part study, a phytotherapeutic preparation from E. laevigatum extract...

journal_title：Advances in therapy

authors： Paulo Filho W,Ribeiro JE,Pinto DS

更新日期：2000-11-01 00:00:00

abstract：:In an open, uncontrolled study, 105 patients with locomotor system symptoms were treated twice daily with an ointment containing a Symphytum active substance complex. A clear therapeutic effect was noted on chronic and subacute symptoms that were accompanied mainly by functional disturbances and pain in the musculatur...

journal_title：Advances in therapy

authors： Kucera M,Kálal J,Polesná Z

更新日期：2000-07-01 00:00:00

abstract：:In this 2-week, randomized, crossover study, ophthalmic solutions of nedocromil sodium 2% and olopatadine hydrochloride 0.1% were compared for effectiveness and acceptability in 28 patients with perennial allergic conjunctivitis and previous olopatadine experience. Patients received nedocromil twice daily or olopatadi...

journal_title：Advances in therapy

authors： Alexander M,Allegro S,Hicks A

更新日期：2000-05-01 00:00:00

abstract：:This multicenter, double-masked, randomized, parallel-group study compared the efficacy and safety of ketorolac tromethamine 0.5% ophthalmic solution with levocabastine 0.05% and ketorolac tromethamine vehicle in patients with seasonal allergic conjunctivitis. One drop of ketorolac, levocabastine, or vehicle was insti...

journal_title：Advances in therapy

authors： Donshik PC,Pearlman D,Pinnas J,Raizman MB,Tauber J,Tinkelman D,Walters TR

更新日期：2000-03-01 00:00:00

abstract：:Clarithromycin, an advanced-generation macrolide antibiotic, has demonstrated excellent in vitro activity against group A beta-hemolytic streptococcus (GABHS). Potent activity against Streptococcus pyogenes and a favorable pharmacokinetic profile have made it a reasonable alternative for treatment of patients with str...

journal_title：Advances in therapy

authors： McCarty J,Hedrick JA,Gooch WM

更新日期：2000-01-01 00:00:00

abstract：:Designed to provide information about patients with schizophrenia who switch from depot neuroleptics to the oral, atypical antipsychotic risperidone, this multicenter observational study enrolled patients who wished to stop the depot, had an unsatisfactory response, or experienced unacceptable side effects. Individual...

journal_title：Advances in therapy

authors： Desai NM,Huq Z,Martin SD,McDonald G

更新日期：1999-03-01 00:00:00

abstract：:In an open, controlled study, 44 patients complaining of vertigo, dizziness, or both, caused by vascular vestibular disorders were randomly treated with extract of Ginkgo biloba (EGb 761) 80 mg twice daily or with betahistine dihydrochloride (BI) 16 mg twice daily for 3 months. A complete neuro-otologic and equilibrim...

journal_title：Advances in therapy

authors： Cesarani A,Meloni F,Alpini D,Barozzi S,Verderio L,Boscani PF

更新日期：1998-09-01 00:00:00

abstract：:Subretinal hemorrhage secondary to age-related macular degeneration (AMD) has a poor visual prognosis. Surgical drainage of the blood improves visual acuity only in selected patients. We report on two elderly patients with spontaneous subretinal hemorrhage from AMD. In one eye, recombinant tissue plasminogen activator...

journal_title：Advances in therapy

authors： Hesse L,Kroll P

更新日期：1997-09-01 00:00:00

abstract：:To avoid the side effects associated with long-term administration of high doses of inhaled glucocorticosteroids, they should be used at the lowest effective dose. This study compared the clinical efficacy of budesonide given via a dry-powder, inspiratory flow-driven device (Turbuhaler), at a daily dose of 800 microgr...

journal_title：Advances in therapy

authors： Piquet J,Zuck P,Dennewald G,Dugue P,Grivaux M,Brun P,Severac JC,Ostinelli J,Cheeseman KH

更新日期：1996-01-01 00:00:00

abstract：:Complicated urinary tract infection (UTI), which often requires hospitalization or prolongs a hospital stay, presents numerous diagnostic and therapeutic challenges. Implementation of effective antimicrobial treatment is vital because of the risk of adverse sequelae due to persistence of infection, relapse, or reinfec...

journal_title：Advances in therapy

authors： Cox CE

更新日期：1995-07-01 00:00:00

abstract：:Patients with reversible bronchospasm benefit from the use of inhaled beta-adrenergic agents. In this retrospective study of 24 older patients with a variety of conditions associated with reversible bronchospasm--asthma, asthma with emphysema, chronic bronchitis, and asthmatic bronchitis--symptomatic improvement was n...

journal_title：Advances in therapy

authors： Messina MS

更新日期：1995-05-01 00:00:00

abstract：:Ambulatory monitoring was used to evaluate the antihypertensive efficacy and effect on circadian rhythms of blood pressure and heart rate of a single dose and long-term administration of ramipril in 20 patients with mild to moderate essential hypertension. Patients initially were randomized to receive either placebo o...

journal_title：Advances in therapy

authors： Cavazzini D,Amadei G,Manfredini R,Musacci G,Mele D,Longhini C

更新日期：1995-01-01 00:00:00

abstract：:Many doubts surround the numerous forms of nonsurgical treatment of nonresectable hepatocellular carcinoma (HCC). Our study aimed to reach reliable conclusions on the actual efficacy of these treatments. We examined 85 studies involving a total of 6746 patients: 6113 were treated; the remaining 633 were not. We applie...

journal_title：Advances in therapy

authors： Malaguarnera M,Trovato G,Restuccia S,Giugno I,Franzé CM,Receputo G,Siciliano R,Motta M,Trovato BA

更新日期：1994-11-01 00:00:00

abstract：:The aims of this study were to determine whether the nursing costs of functional disability could be assessed retrospectively and, if so, whether this method was sensitive enough to show the influence of a treatment on economic costs. Four studies were available for this purpose: three randomized, double-blind, place...

journal_title：Advances in therapy

authors： Vlietinck R,Van Loon H,Van de Broele H,Tormans G

更新日期：1993-09-01 00:00:00

abstract：:Available data from comparative trials involving 483 patients were analyzed to determine the rate of infectious morbidity following the use of absorbable staples versus traditional incision and suturing of the vaginal cuff in abdominal hysterectomy. Infections occurred in 24 of 268 (9%) patients who received absorbab...

journal_title：Advances in therapy

authors： Martens MG,Shailer LD

更新日期：1991-05-01 00:00:00